USF Polytechnic is an integral part of the University of South Florida system, a highly regarded public research university with a commitment to community engagement. USFP enjoys collaborative relationships with each of the institutions within the USF system:

USF's Tampa campus, including USF Health, is located in Northeast Tampa. Nearly 39,000 students attend classes on the Tampa campus.

USF St. Petersburg is located on the waterfront in beautiful downtown St. Petersburg. USFSP and offers a complete four-year residential college experience, including 26 undergraduate degrees and 12 graduate degrees.

USF Sarasota-Manatee is located on a beautiful new campus on the border of Sarasota and Manatee counties and offers 42 upper level undergraduate, graduate, and certificate programs.